Pharmacotherapy for personality disorders

Evidence-based pharmacotherapy for personality disorders.

Patients with personality disorders are prescribed psychotropic medications with greater frequency than almost any other diagnostic group. Prescribing practices in these populations are often based on anecdotal evidence rather than rigorous data. Although evidence-based psychotherapy remains an integral part of treatment, Axis II psychopathology is increasingly conceptualized according to neuro...

Recent approaches to pharmacotherapy of personality disorders

Pharmacotherapy for acid/peptic disorders.

In the 1970s, the identification of the histamine H2-receptor by Black and the subsequent development of histamine H2-receptor antagonists revolutionized our understanding and treatment of acid/peptic disorders. More recently, the identification of hydrogen-potassium-stimulated adenosine triphosphatase (H+/K(+)-ATPase) as the proton pump of the parietal cell and the recognition of the prominent...

Pharmacotherapy for borderline personality disorder: NICE guideline.

In their review of drug treatments for borderline personality disorder, Lieb et al, 1 despite considering similar evidence, draw largely different conclusions from those we drew when developing the National Institute for Health and Clinical Excellence (NICE) guideline. 2 Lieb et al recommend a range of drugs. These include anticonvulsants for affective dysregulation symptoms (topiramate, valpro...

Combination of psychodynamic psychotherapy and pharmacotherapy for patients with Personality Disorders: recent findings.

From the 80s onwards, new psychotherapeutic interventions were developed to achieve profound changes to the character pathology of the most serious cases with Personality Disorders, utilizing the existing psychiatric settings (inpatient wards or day hospitals). The latter were taken as the necessary framework (or containing, in psychoanalytic terminology) parameter for dealing with the enactmen...